Registration Dossier

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: data submitted by ECHA
Title:
Unnamed
Year:
1989

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Ames
Principles of method if other than guideline:
see original notification dossier
GLP compliance:
yes
Type of assay:
bacterial reverse mutation assay

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Test results
Species / strain:
other: S. typhimurium TA98, TA 100, TA 1535, TA 1537, TA1538
Metabolic activation:
with and without
Genotoxicity:
other: see original notification dossier
Cytotoxicity / choice of top concentrations:
other: see original notification dossier

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
positive with metabolic activation
positive without metabolic activation