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Adsorption / desorption

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Description of key information

Results from QSAR computations indicate that the estimated log Koc of the substance is around 10.5140. The substance is not within the applicability domain. The free acid of the test substance was used for the calculation.

Key value for chemical safety assessment

Koc at 20 °C:
32 658 783 217

Additional information

Following Koc QSAR data have been derived from EPI Suite: First Order Molecular Connectivity Index log Koc was calculated to be 10.5140 and KOC to be 1E+010 L/kg repectively. Using the KOW method the log KOC was calculated to be 5.4189 and the KOC to be 2.624E+005 L/kg respectively. The values were calculated for the freee acid of the test substance. The data showed that the free acid of the substance is not within the applicability domain.


In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.

According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.

For the assessment of [mu-[[3,3'-[(1-oxido-1,2-diazenediyl)bis[[2-(hydroxy-kappa-O)-4,1-phenylene]-2,1-diazenediyl-kappa-N1]]bis[4-(hydroxy-kappa-O)-2,7-naphthalenedisulfonato]](8-)]]dicopper, tetrasodium salt (Q)SAR results were used for Adsorption / desorption.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.

Therefore, further experimental studies on adsorption / desorption are not provided.

[LogKoc: 10.514]