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Environmental fate & pathways

Adsorption / desorption

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Description of key information

Adsorption to solid soil phase is expected. 

Key value for chemical safety assessment

Additional information

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.

 

According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.

 

For the assessment of CAS 976 -56 -7 (Q)SAR results were used for adsorption/desorption.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.

 

Therefore, further experimental studies on adsorption/desorption are not provided.

The adsorption/desorption potential of the compound was assessed with two different QSAR methods. The compound was within the applicability domain of both compounds. The MCI method revealed a logKoc of 3.7 whereas the estimate from logKow revealed a logKoc of 3.1. In conclusion, adsorption to solid soil phase is expected.