Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 931-313-9 | CAS number: -
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Type of information:
- other: epidemiology study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: MIGRATED DATASET. Original reference not available.
Data source
Reference
- Title:
- No information
- Author:
- DuPont (1985). Mortality and cancer incidence among workers exposed to 1,4-dichlorobutene-2 at the Victoria plant. Haskell Laboratory, Epidemiology Section, medical Division, Employee Relations Department. Report from January 1985 (NTIS OTS 509754).
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,4-dichlorobut-2-ene
- EC Number:
- 212-121-8
- EC Name:
- 1,4-dichlorobut-2-ene
- Cas Number:
- 764-41-0
- Molecular formula:
- C4H6Cl2
- IUPAC Name:
- 1,4-dichlorobut-2-ene
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not specified
- Details on study design:
- An epidemiology study was conducted on 598 male workers exposed to 1,4-dichlorobut-2 ene at the Victoria plant of DuPont Co. in Texas, USA from 1956 through 1983 for cancer incidence, and from 1957 through 1980 for mortality.
Results and discussion
- Results:
- By comparing the mortality and cancer rates of the DuPont Company with the US national rates, the results did not indicate that employees are at an increased risk of developing cancer.
- Strengths and weaknesses:
- The validity of this study suffers from its limited statistical power due to the small size of the cohort.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
