Registration Dossier
Registration Dossier
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EC number: 931-313-9 | CAS number: -
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
- Reference Type:
- secondary source
- Title:
- 1,4-Dichlorobut-2-ene - CAS No: 764-41-0
- Author:
- OECD SIDS
- Year:
- 2 006
- Bibliographic source:
- SIDS Initial Assessment Report for 22th SIAM, UNEP Publications
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- Principles of method if other than guideline:
- EU Method C.11 is in most parts identical with OECD TG 209
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- IUCLID4 Test substance: other TS: 1,4-Dichlorobut-2-ene, purity 96.1 % (31.9 % cis- and 64.2 % trans-isomer)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- Details on test conditions:
- Type: aquatic
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 573 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Any other information on results incl. tables
RS-Freetext:
1,4-Dichlorobut-2-ene showed 95.6 % respiration inhibition of activated sludge at a test substance concentration of 10000 mg/l.
The test substance and reference substance concentrations are not confirmed by analytical methods. They are based on nominal concentrations
Applicant's summary and conclusion
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