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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
other: Migrated dataset
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Adopted according to OECD SIDS. The original source is not available and has not been reviewed.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
1,4-Dichlorobut-2-ene - CAS No: 764-41-0
Author:
OECD SIDS
Year:
2006
Bibliographic source:
SIDS Initial Assessment Report for 22th SIAM, UNEP Publications
Reference Type:
review article or handbook
Title:
Handbook of Environmental Data on Organic Chemicals (3rd ed.)
Author:
Verschueren (as cited in OECD SIDS)
Year:
1996
Bibliographic source:
Van Nostrand Reinhold, New York
Reference Type:
publication
Title:
Joint Toxicity of Mixtures of Groups of Organic Aquatic Pollutants to the Guppy (Poecilia reticulata).
Author:
Hermens, J, Busser, F. Leeuwangh, P., Musch, A. (as cited in OECD SIDS)
Year:
1985
Bibliographic source:
Ecotoxicology and Environmental Safety 9, 321-326
Reference Type:
publication
Title:
Quantitative structure-activity relationships and mixture toxicity of organic chemicals in Photobacterium phosphoreum. The microtox Test.
Author:
Hermens, J, Busser, F. Leeuwangh, P., Musch, A. (as cited in OECD SIDS)
Year:
1985
Bibliographic source:
Ecotoxicology and Environmental Safety 9, 17-25
Reference Type:
publication
Title:
Theoretical descriptors for the correlation of aquatic quantitative structure-toxicity relationships.
Author:
Katritzky A R, Tatham DB, Maran U (as cited in OECD SIDS)
Year:
2001
Bibliographic source:
J. Chem. Inf. Sci. 41 (5), 1162-1176

Materials and methods

Principles of method if other than guideline:
other: test procedure according to Koenemann H (1981). Toxicology 19, 209-221.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): trans-1,4-dichlorobut-2-ene
- purity > 95 %

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Poecilia reticulata

Study design

Test type:
semi-static

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
0.086 mg/L

Any other information on results incl. tables

RS-Freetext:
LC50 values were calculated according to Litchfield and Wilcoxon ((1949).  A simplified method of evaluating dose-effect experiments. J. Pharmacol.  Exp. Ther. 96, 99-113, ) or in case of a steep concentration-effect  relationship by estimating using a log/probit plot.
Experimentally determined log LC50 value (14d): -0.16 µmol/l  (corresponding to LC50 (14d): 0.0864 mg/l)

Applicant's summary and conclusion