Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 811-484-5 | CAS number: 680972-33-2
Toxicity to reproduction
Administrative data
- Endpoint:
- extended one-generation reproductive toxicity - basic test design (Cohorts 1A, and 1B without extension)
- Remarks:
- Test on going
- Type of information:
- other: Read across from category (Hydrotropes)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 443 (Extended One-Generation Reproductive Toxicity Study)
- GLP compliance:
- yes
- Limit test:
- no
- Justification for study design:
- ECHA requests based on compliance check of the category Hydrotropes
Test material
- Reference substance name:
- Sodium (xylenes and 4-ethylbenzene) sulfonate
- EC Number:
- 701-247-3
- Molecular formula:
- -
- IUPAC Name:
- Sodium (xylenes and 4-ethylbenzene) sulfonate
- Details on test material:
- Purity > 94.8%
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male/female
Results and discussion
Results: P0 (first parental generation)
Effect levels (P0)
- Remarks on result:
- other: Test on going
Results: P1 (second parental generation)
Effect levels (P1)
- Remarks on result:
- other: Test on going
Results: F1 generation
Effect levels (F1)
- Remarks on result:
- other: Test on going
Results: F2 generation
Effect levels (F2)
- Remarks on result:
- not measured/tested
Overall reproductive toxicity
- Reproductive effects observed:
- no
Applicant's summary and conclusion
- Conclusions:
- Test on going on similar substance
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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