Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1992
Report date:
1992

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dihydroxy-4-methyl-1-[3-(methylaminio)propyl]pyridine-1-sulfate salt
EC Number:
931-673-7
Cas Number:
1333469-72-9
Molecular formula:
C10 H18 N2 O6 S1
IUPAC Name:
2,6-dihydroxy-4-methyl-1-[3-(methylaminio)propyl]pyridine-1-sulfate salt

Results and discussion

In vivo

Results
Irritation parameter:
erythema score
Basis:
mean
Time point:
other: 4 h
Score:
< 1.3

Applicant's summary and conclusion

Interpretation of results:
slightly irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU