Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 272-905-0 | CAS number: 68919-79-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Under the study conditions, the LOEC, EC50 (growth rate) and EC50 (yield) of the test substance were 1, 24 and 3.6 mg/L, respectively.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 24 mg/L
Additional information
A study was conducted to assess the toxicity of the test substance to the green algae Desmodesmus subspicatus according to OECD Guideline 201 and EU Method C.3, in compliance with GLP. Given the low water solubility of the substance, algae were exposed to water accommodated fractions at nominal loading rates of 0, 1.0, 3.2, 10, 32 and 100 mg/L and an incubation time of 72 h. The cell concentration of each replicate was determined by measuring the absorption of the solutions at 440 nm every 24 h with a spectral photometer. Cell density was calculated based on the correlation curve between the absorption and the cell density of the cultures determined with a cell counter. Growth rate and yield were determined from the cell densities at the respective observation times. Presence of test material was confirmed by Dissolved Organic Carbon (DOC) analysis. Significant inhibition of algal growth was observed at all concentrations. All the validity criteria was met. Under the study conditions, the LOEC, EC50 (growth rate) and EC50 (yield) of the test substance were 1, 24 and 3.6 mg/L, respectively (Muckle M, 2015c).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
