Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

The analogue substance was tested for potential genetic toxicity in an in-vitro test (Ames test, EU Mehtod ) and in one in-vivo test (Micronucleus), providing negative results.

Based on the read across considerations the same applies to Acid Black 233:2 whose genotoxic potential is considered negative.

Short description of key information:
Ames test, 5 strains, with and without S9, negative
in vivo Micronucleus, mouse (male), 2000 mg/kg bw, negative

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Based on the test results the substance is not classified for genotoxicity under Regulation 1272/2008