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Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1988
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Testing according to OECD209

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1989

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: EEC-guideline 88/302C
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methyl-1-p-tolyl-5-pyrazolone
EC Number:
201-708-4
EC Name:
3-methyl-1-p-tolyl-5-pyrazolone
Cas Number:
86-92-0
Molecular formula:
C11H12N2O
IUPAC Name:
3-methyl-1-p-tolyl-5-pyrazolone

Test solutions

Details on test solutions:
Due to the low water solubility no stock solution was used. The test item was weighed out directly into the test vessels.

Test organisms

Test organisms (species):
activated sludge

Study design

Total exposure duration:
3 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
76.3 mg/L
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
818.1 mg/L
Duration:
3 h
Dose descriptor:
EC100
Effect conc.:
> 1 000 mg/L

Applicant's summary and conclusion

Conclusions:
The EC50 of the tested substance to activated sludge is 818.1 mg/L.