CJ303

Endpoint summary

Description of key information

The 96-hr LC50 of CJ303 was 9375 mg/L for fish (OECD TG203).

The 48-hr EC50 of CJ303 was >100 mg/L for Daphnia magna (OECD TG202).

E_rC₅₀and the E_yC₅₀of CJ303 was >100 mg/L and 49.62mg/L for Pseudokirchneriella subcapitata, respectively (OECD TG201).

Additional information

This study was conducted according OECD203:2019 to evaluate the lethal effect of test article on zebrafish (Danio rerio). The results indicated that under the conditions designed for this test, CJ303 was not lethal to zebrafish. Its NOEC was 100.00 mg/L nominal concentration.

In both range-finding and limit test, not more than 10 % of the Daphnia were immobilised in the control and the dissolved oxygen concentration at the end of the test was ≥3 mg O₂/L. All test validity criteria were met. The pH of the test solutions was within the ranges outlined in the OECD 202 test guideline. Under the conditions of this test, the 48-hr EC50 of CJ303 was >100 mg/L.

An alga growth inhibition test was conducted according to OECD 201:2011 to evaluate growth inhibition caused by CJ303. The test system wasPseudokirchneriella subcapitata. According to OECD201:2011, the concentration series should cover the range causing 5-75% inhibition of alga growth rate. If there was no growth inhibition occurred at 100 mg/L, the highest concentration was 100 mg/L. In the range-finding test, the test article concentration of 100.00-0.16 mg/L was used which covered a range of -4.07~1.16% inhibition in average specific growth rate, so the limit test was conducted. In the limit test, the test article concentrations applied was 100.00 mg/L. The results showed that, in days 0-3, the percent inhibition in average specific growth rate was a range of 18.08~26.41%, and the percent inhibition of yield was a range o 53.66~67.67%. Therefore, under these test conditions, the E_rC₅₀of CJ303 forPseudokirchneriella subcapitatawas greater than 100.00 mg/L and E_yC₅₀was 49.62 mg/L.