Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

A skin sensitisation test for this substance is waived as the constituent Cinnamic aldehyde - trans (CAS 14371-10-9), present at a typical concentration of 77%, is currently classified as H317 (Skin Sens. 1). Based on this information Cassia oil is considered to be classified as H317 (Skin Sens. 1) as well and therefore further testing is deemed not required. This conclusion is supported by an available publication (Klecak, 1985) in which 4% Cassia oil was found to be sensitising in human (hRIPT) and guinea pigs (OET).

Migrated from Short description of key information:

Read-across based on classification of main constituent: sensitising

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Based on the skin sensitising properties of the major constituent of Cassia oil, the substance needs to be classified for Skin Sensitisation (Skin Sens. 1; H317) in accordance with the criteria outlined in Annex I of 1272/2008/EC (CLP/EU-GHS).