Registration Dossier

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to international accepted guidelines, but not GLP compliant.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
Test item: 4-Chloro-4’-fluorobutyrophenoneCAS number: 3874-54-2EC number: 223-395-3Molecular formula: C10H10ClFOMolecular weight: 200.64 g/molSupplier: Sigma-AldrichBatch number STBD6247VPhysical state: liquidColour: Dark yellowStorage: cool, dry place in a tightly closed container

Results and discussion

Water solubility
Water solubility:
0.111 g/L
Temp.:
30 °C
pH:
2.51 - 2.53
Remarks on result:
other: 24-hour result
Details on results:
The test item is very unstable in aqueous solution. The insoluble particles disappeared from the emulsion during 48 hours while the concentration of the test item decreased in the solution.Because of fast degradation, the results of first measurement (after 24 h) were used only for determination of water solubility.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)