2,4-Pyrimidinediamine, 6-chloro-, 3-oxide

Boiling point

Administrative data

Endpoint:

boiling point

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid which decomposes before boiling

Justification for type of information:

In accordance with the Column 2 of REACH Annex VII, the study does not need to be conducted for solids which decompose before boilingµ. As observed in the study conducted to estimate the melting point of the test item, decomposition occured at temperature below the boiling point of the test item.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

-

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

-

Deviations:

no

GLP compliance:

no

Type of method:

capillary method

Specific details on test material used for the study:

- Analytical purity: > 99%- Lot/batch No.: 0160405- Expiration date of the lot/batch: 21/02/2018

Key result

Atm. press.:

ca. 1 atm

Decomposition:

yes

Decomp. temp.:

ca. 179.9 °C

Pre-Test

Begin of changes was visible at 192.7 °C (getting darker). The test substance was completely black at 195.3 °C. The last changes were nearly explosively.Decomposition was stated.

Main Study

The following values were recorded:

Values Main Study

Decomposition	Begin	End
First determination	180.0 °C (453.2 K)	182.2 °C (455.4 K)
Second determination	179.9 °C (453.1 K)	181.7 °C (454.9 K)

Validity

As the test substance decomposes no validity criteria must be considered.

Result

The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test substance.

 

Beginning decomposition was determined with

 179.9 °C (453.1 K)

 Signs for explosive properties were visible.

Conclusions:

The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test substance. Beginning decomposition was determined with 179.9 °C (453.1 K). Signs for explosive properties were visible.

Executive summary:

The melting point of the test item was investigated with a not-GLP compliant study, following the standard guideline OECD TG 102 (capillary method). The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test item. Beginning decomposition was determined with 179.9 °C (453.1 K). Signs for explosive properties were visible.