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Data on the stability of quinic acid are only available for phototransformation. The calculated phototransformation in air, calculated from the hydroxyl radical turn over rate is 40.6288 E-012 cm^3/molecule/s (0.00000351 cm^3/molecule/d). Therefore, we consider phototransformation in air to be negligible. These results are calculated using AOP v1.92, expecting, that phototransformation appears at a constant rate. The EPA recommends that empirical measures provide better results. However, empirical studies have not been done, so that we adapt the prediction.


Quinic acid was tested in a CO2 Evolution Test according to the OECD Guideline 301 B for 28 days (and 29 days after acidification) to determine whether the test substance is readily biodegradable. The degradation extent of quinic acid reached 89.7% by the end of the test (mean of three replicates). On day 4 the degradation of quinic acid reached already 65.3%. The reference compound sodium benzoate reached the pass levels for ready biodegradability within 4 days. The degradation in the toxicity control after 4 days was 70.0% and thus above the criterion for inhibition effects to the inoculum. Quinic acid had no toxic effect to the inoculum according to the validity criteria of OECD 301 on ready biodegradability. Quinic acid reached the criteria for ready biodegradability (60% ThCO2 and10-day time window). Therefore, it can be concluded that quinic acid is readily biodegradable.


The given BCF, BAF and Biotransformation half-life estimations from the models for quinic acid show, that quinic acid has a low accumulation potential. Nevertheless, the EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available. However, empirical studies have not been done, so that we consider a BCF of 3.16 L/kg, BAF of 0.893 L/kg and Biotransformation half-life of 0.00221 days.

Transport and distribution:

The EPI Suite v.4.11. results show that, the adsorption of quinic acid is low. The major amount is distributed to soil and water. The estimated Henrys law constant of quinic acid is 7.69E-007 Pa-m3/mole.