Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-112-3 | CAS number: 606-28-0
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance is not readily biodegradable in a Manometric Respirometry Test according to OECD 301F. Hydrolysis studies of the substance indicate that test item is stable at pH 4, but hydrolyses at pH 7 and 9. Hydrolysis was fastest at pH 9 and 50°C, and slowest at pH 7 and 15°C. The substance has a half-life of 70.8 days at pH 7 and 25 °C. At pH 7 and 15°C, the half-life of the substance is 243 days. Hydrolysis products have not been determined. Therefore the substance fulfils the criteria of persistent (P).
Based on the results of Combined Repeated Dose Toxicity Study/Reproduction/Developmental Toxicity Screening Test (OECD 422), the substance has been self-classified for specific target organ toxicity after repeated exposure as STOT RE Category 2 (H373), according to Regulation EC No 1272/2008. Therefore the substance fulfils the criteria of toxic (T).
The substance does not have B or vB properties as the low Kow is 2.8. Moreover, EpiWIN predicts a BCF of 7.3 which is clearly below 2000. This confirms that the substance has no potential for significant bioaccumulation and does not need to be defined as “B” or “vB”.
In conclusion, the substance does not fulfil all criteria for PBT or vPvB according to Annex XIII of Regulation EC No. 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
