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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 5, 2014 - May 21, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-compliant study in accordance with EC A.6, OECD 105 and OPPTS 830.7840.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(2008)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
(1995)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
(1998)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Strontium tartrate
EC Number:
212-774-9
EC Name:
Strontium tartrate
Cas Number:
868-19-9
Molecular formula:
C4H4O6Sr
IUPAC Name:
strontium(2+) 2,3-dihydroxybutanedioate
Details on test material:
- Name of test material (as cited in study report): Strontium Tartrate (anhydrous)
- Appearance: Off-white powder

Results and discussion

Water solubility
Water solubility:
1.86 g/L
Temp.:
20 °C
pH:
>= 6.8 - <= 6.9
Remarks on result:
other: Mean of the concentrations analysed at t=24, 48 and 72 h.
Details on results:
No test substance was detected in the pre-treated sample from the blank water mixture.
Concentrations analysed at t=24, 48 and 72 h: 1.85 g/L, 1.84 g/L and 1.88 g/L, resp.
The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15% (2.2% was calculated), thus the validity criterion is met.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
In a GLP-compliant study in accordance with EC A.6, OECD 105 and OPPTS 830.7840 using the flask method, the water solubility of the substance at 20°C was determined as 1.86 g/L. The pH of the saturated solution was 6.8-6.9.