Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 5, 2014 - May 21, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-compliant study in accordance with EC A.1, OECD 102 and EPA OPPTS 830.7200.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
(2008)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
(1995)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
(1998)
Deviations:
no
GLP compliance:
yes
Type of method:
thermal analysis
Remarks:
(differential scanning calorimetry)

Test material

Constituent 1
Chemical structure
Reference substance name:
Strontium tartrate
EC Number:
212-774-9
EC Name:
Strontium tartrate
Cas Number:
868-19-9
Molecular formula:
C4H4O6Sr
IUPAC Name:
strontium(2+) 2,3-dihydroxybutanedioate
Details on test material:
- Name of test material (as cited in study report): Strontium Tartrate (anhydrous)
- Appearance: Off-white powder

Results and discussion

Melting / freezing point
Decomposition:
yes
Decomp. temp.:
> 250 °C
Remarks on result:
other: No melting before decomposition started. Decomp. temp. in K: > 523

Any other information on results incl. tables

PRELIMINARY TEST WITH TGA

From 250°C upwards the weight of the sample decreased significantly. At 428°C the sample weight had decreased by 25%. After the experiment, a brown/black residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test substance.

DSC EXPERIMENT

No effects were obtained which were due to melting of the test substance. The observed endothermic and exothermic peaks (from 250°C onwards) were due to reaction and/or decomposition of the test substance based on the shape of the heat flow curve. After the experiment, a brown residue remained in the sample container.

Applicant's summary and conclusion

Conclusions:
In a GLP-compliant study in accordance with EC A.1, OECD 102 and EPA OPPTS 830.7200 using differential scanning calorimetry, melting was not observed before decomposition of the substance started at 250°C. It was therefore concluded that the substance has no melting temperature.

Categories Display