Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 212-512-3 | CAS number: 823-36-9
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- QSAR Toolbox 3.1.0.21
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- VegaNIC - Vega Non - Interactive Client - version 1.0.8
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- T.E.S.T. version 4.1
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- ChemProp - QSAR 6 Public OSIRIS Edition
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-ethylcyclopentane-1,3-dione
- EC Number:
- 212-512-3
- EC Name:
- 2-ethylcyclopentane-1,3-dione
- Cas Number:
- 823-36-9
- Molecular formula:
- C7H10O2
- IUPAC Name:
- 2-ethylcyclopentane-1,3-dione
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 740.03 mg/L
- Nominal / measured:
- estimated
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Software Database / Method Endpoint Test duration Species Predicted value QSAR Toolbox Aquatic OASIS LC50 96 h Pimephales promales 279 mg/l VegaNIC N.A. LC50 96 h Fathead minnow 178.94 mg/l VegaNIC N.A. Alerts - - NON Toxic T.E.S.T. FDA Method LC50 96 h Fathead minnow 595.93 mg/l T.E.S.T. Nearest neighbor method LC50 96 h Fathead minnow 1325,22 mg/l ChemProp Van Leeuwen et al model LC50 96 h Fathead minnow 1321.06 mg/l
Applicant's summary and conclusion
- Conclusions:
- According to (Q)SAR modells: QSAR Toolbox, VegaNIC, T.E.S.T., ChemProp the predicted values indicated that Ethyl-cyclopentanedione is not hazardous to fish. The result does not meet the requirement of any Aquatic Acute Category.
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