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EC number: 800-253-4 | CAS number: 1419212-73-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24-04-2013 to 23-05-2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: according to the guideline, under GLP
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Principles of method if other than guideline:
- The test substance was prepared by High Shear Mixing (7500 rpm for 15 minutes)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Severn Trent Water Plc sewage treatment plant Loughborough, Leicesterhire, UK
- Storage conditions: under aeration at 21 °C
- Storage length: <1 day
- Preparation of inoculum for exposure: washed twice by settlement and resuspended thereafter
- Pretreatment: none
- Concentration of sludge: suspended solids 3.1 g/L - Duration of test (contact time):
- 29 d
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to guideline
- Solubilising agent (type and concentration if used): none
- Test temperature: 21 °C
- pH: 7.2-7.6 (at day 0 after adjustment and day 28)
- pH adjusted: yes in all vessels
- Aeration of dilution water: yes
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes
TEST SYSTEM
- Number of culture flasks: 2 test substance +inoculum, 2 inoculum, 2 reference substance + inoculum, 1 toxicity control
- Method used to create aerobic conditions: bubbling of CO2-free air at 30-100 mL/min
- Details of trap for CO2 and volatile organics: 2 NaOH CO2-traps (Drechsel)
SAMPLING
- Sampling frequency:
CO2 on day 0, 2, 6, 8, 10, 14, 21, 28, 29 (second trap on day 0 and 29) analyses in triplicate
IC: on day 0 (stated to be not possible bacause of insolubility of the test item, but measurements included show accuracy within 5% of TC)
- Sterility check if applicable: not included
- Sample storage before analysis: none
CONTROL AND BLANK SYSTEM
- Inoculum blank: in duplicate
- Abiotic sterile control: not included
- Toxicity control: single vessel with test substance + reference substance + inoculum (20 mg C/L)
STATISTICS
student's t-test - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 0 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 29 d
- Remarks on result:
- other: after acidification of the medium
- Details on results:
- Test solutions all were pale brown dispersions. No undissolved test substance was visible.
- Results with reference substance:
- Degradation 62% on day 29
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance attained 0 % degradation after 29 days and is therefore considered not readily biodegradable.
- Executive summary:
The test substance was tested in a CO2 evolution test for 29 days. The test substance attained 0% degradation and is therefore considered not readily biodegradable.
Reference
Description of key information
The test substance was tested in a CO2 evolution test for 29 days. The test substance attained 0% degradation and is therefore considered not readily biodegradable (Harlan 2013).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
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