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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
13-ethyl-3-methoxygona-2,5(10)-dien-17β-ol
EC Number:
238-513-9
EC Name:
13-ethyl-3-methoxygona-2,5(10)-dien-17β-ol
Cas Number:
14507-49-4
Molecular formula:
C20H30O2
IUPAC Name:
(1S,3aS,3bR,9bS,11aS)-11a-ethyl-7-methoxy-1H,2H,3H,3aH,3bH,4H,5H,6H,9H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-ol
Test material form:
solid: crystalline
Details on test material:
Test item: Gonol
CAS number: 14507-49-4
Batch number: 252156N
Physical state: Solid, crystalline substance
Colour: White
Storage: At a temperature of 15 to 30 °C

Results and discussion

Water solubility
Key result
Water solubility:
325 µg/L
Conc. based on:
test mat.
Temp.:
22.5 °C
pH:
5

Applicant's summary and conclusion

Conclusions:
Preliminary phase the estimated water solubility was 0.000087 g/l. As the estimated solubility of the test item was lower than 0,01 g/l, so the column elution method was applied int he second phase of the test.
The solubility was determined at 259 and 140 ml/hour flow rates. The average water solubility of Gonol is 0.000325 g/l.