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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1975
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
no
Specific details on test material used for the study:
None
Analytical monitoring:
no
Details on sampling:
Not available
Vehicle:
not specified
Details on test solutions:
None
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Details on test organisms:
TEST ORGANISM
- Common name: Rainbow Trout
Test type:
not specified
Water media type:
not specified
Limit test:
no
Total exposure duration:
96 h
Post exposure observation period:
No data
Hardness:
No data
Test temperature:
No data
pH:
pH 7-8
Dissolved oxygen:
No data
Salinity:
No data
Nominal and measured concentrations:
0.2, 2, 100 and 200 mg/L
Details on test conditions:
No data
Reference substance (positive control):
no
Duration:
48 h
Dose descriptor:
other: TL0
Effect conc.:
0.2 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
1.3 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
20 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Details on results:
None
Results with reference substance (positive control):
None
Reported statistics and error estimates:
No data
Sublethal observations / clinical signs:

No mortality was seen with the test concentration 0.2 mg/L. While 5 out of 8 fish were found dead when exposed to 2 mg/l. At 20 and 100 mg/L, all the fish exposed were found dead.

Validity criteria fulfilled:
not specified
Conclusions:
The 48 h LC50 was found to be 1.3 mg/L.
Executive summary:

The short term toxicity of FAT 20077/A was evaluated in a study conducted using methodology similar OECD Guideline 203. Three groups of containing 8 fish each were exposed to test concentrations of 0.2, 2, 20 and 100 mg/L for 48 hours. No mortality was seen with the test concentration 0.2 mg/L. While 5 out of 8 fish were found dead when exposed to 2 mg/l. At 20 and 100 mg/L, all the fish exposed were found dead. Based on these findings, the following results were obtained:

TL0 (48 h): 0.2 mg/L

TL50 (48 h): 1.3 mg/L

TL100 (48 h): 20 mg/L

Description of key information

The short term toxicity of FAT 20077/A was evaluated in a study conducted using methodology similar OECD Guideline 203. Three groups of containing 8 fish each were exposed to test concentrations of 0.2, 2, 20 and 100 mg/L for 48 hours. No mortality was seen with the test concentration 0.2 mg/L. While 5 out of 8 fish were found dead when exposed to 2 mg/l. At 20 and 100 mg/L, all the fish exposed were found dead. Based on these findings, the following results were obtained:

TL0 (48 h): 0.2 mg/L

TL50 (48 h): 1.3 mg/L

TL100 (48 h): 20 mg/L

In couple of supporting studies evaluating short term toxicity to fish, the 48 H TL50 obtained were 3.2 and 4.4 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1.3 mg/L

Additional information