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Partition coefficient

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Description of key information

log Pow = 8.474 (OECD 117)
log Pow > 10 (KOWWIN v1.68)

Key value for chemical safety assessment

Additional information

The log Pow of the substance Propyleneglycol dioleate (CAS 105 -62 -4) was determined according to OECD 117 by HPLC method.

Due to the use of reference substances with lower log Pow (max. log Pow = 5.7, triphenylamine) the final result had to be extrapolated from the calibration equation with R2 = 0.6651. This result is therefore supported by QSAR calculation with KOWWIN v1.68.

The log Pow =16.11 of the substance Propyleneglycol dioleate (CAS 105-62-4) was determined by QSAR calculation for the main component C18:1 diester with propylene glycol. Due to the fact that this substance is long chain fatty acid ester which exceeds the applicability domain of KOWWIN the value for log Pow is reported with restrictions.Therefore the partition coefficient of the substance is deduced to be > 10.