Registration Dossier
Registration Dossier
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A mixture of Propanoic acid, -1-methyl, 2-hydroxy-, (C12-14)-alkyl ester, Propanoic acid, 2-hydroxy-, 2-(C12-14-alkyloxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(2-(2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoeth oxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester, Propanoic acid, 2-hydroxy-, 2-(2-(2-(2-(2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoeth oxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester and Propanoic acid, 2-hydroxy-, 2-(2-(2-(2-(2-(2-(2-(2-(C12-14-alkyloxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoeth oxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethoxy)-1-methyl-2-oxoethyl ester
EC number: 941-488-3 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In an acute toxicity test performed in accordance with OECD TG 201 using Pseudokirchneriella subcapitata, the 96-h ErC50 value was > 1 mg/L and the NOErC was 0.30 mg/L, based on nominal concentrations. The 72-h ErC50 was 0.61 mg/L and the NOEC was 0.09 mg/L. The 96 -h values override the 72 -h values, hence it may be considered that the ErC50 is higher than the water solubility and the NOErC is equal to the water solubility.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 0.3 mg/L
Additional information
In a 96-hour algal inhibition study performed in accordance with OECD TG 201, EU Method C3 and US OPPTS 850.5400,
Pseudokirchneriella subcapitata were exposed to the substance, dissolved in DMF, at nominal concentrations of 0.0081, 0.027, 0.09, 0.3 and 1.0 mg/L. The dose concentrations were chosen based on the results of a preliminary toxicity study. A blank control and a solvent control was run in conjunction with the final test. The study met the acceptability criteria and was considered valid.
The 96-h ErC50 value was > 1 mg/L and the EbC50 value was 0.69 mg/L based on nominal dose concentrations. The NOEC for growth rate and biomass was 0.30 mg/L. The 72-h ErC50 was 0.61 mg/L and the NOEC was 0.09 mg/L.
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