Registration Dossier

Diss Factsheets

Administrative data

First-aid measures

Description of first aid measures.

EYES: Remove contact lenses, if present. Wash immediately with plenty of water for at least 15 minutes, opening the eyelids fully. If problem persists, seek medical advice.

SKIN: Remove contaminated clothing. Wash immediately with plenty of water. If irritation persists, get medical advice/attention. Wash contaminated clothing before using it again.

INHALATION: Remove to open air. In the event of breathing difficulties, get medical advice/attention immediately.

INGESTION: Get medical advice/attention. Induce vomiting only if indicated by the doctor. Never give anything by mouth to an unconscious person, unless authorised by a doctor.

Most important symptoms and effects, both acute and delayed.

For symptoms and effects caused by the contained substances, see toxicological information.

According to currently available data, this product has not yet produced health damages. Anyway, it must be handled according to good industrial practices. The product has an antihypertensive and antialopecia activity.

Indication of any immediate medical attention and special treatment needed.

Information not available.

Fire-fighting measures

Extinguishing media.


The extinguishing equipment should be of the conventional kind: carbon dioxide, foam, powder and water spray.


None in particular.

Special hazards arising from the substance or mixture.


Do not breathe combustion products. The product is combustible and, when the powder is released into the air in sufficient concentrations and in the presence of a source of ignition, it can create explosive mixtures with air. Fires may start or get worse by leakage of the solid product from the container, when it reaches high temperatures or through contact with sources of ignition.

Advice for firefighters.


Use jets of water to cool the containers to prevent product decomposition and the development of substances potentially hazardous for health. Always wear full fire prevention gear. Collect extinguishing water to prevent it from draining into the sewer system. Dispose of contaminated water used for extinction and the remains of the fire according to applicable regulations.


Normal fire fighting clothing i.e. fire kit (BS EN 469), gloves (BS EN 659) and boots (HO specification A29 and A30) in combination with self-contained open circuit positive pressure compressed air breathing apparatus (BS EN 137).

Accidental release measures

Personal precautions, protective equipment and emergency procedures.

If there are no contraindications, spray powder with water to prevent the formation of dust. Avoid breathing vapours/mists/gases.

Wear suitable protective equipment to prevent any contamination of skin, eyes and personal clothing. These indications apply for both processing staff and those involved in emergency procedures.

Environmental precautions.

The product must not penetrate into the sewer system or come into contact with surface water or ground water.

Methods and material for containment and cleaning up.

Use spark-proof mechanical equipment to collect the leaked product and place it in containers for recovery or disposal. If there are no contraindications, use jets of water to eliminate product residues.

Make sure the leakage site is well aired. Check incompatibility for container material. Contaminated material should be disposed of in compliance with the provisions set forth by national waste management regulations.

Handling and storage

Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at

places where dust is formed. Normal measures for preventive fire protection.

Conditions for safe storage, including any incompatibilities.

Store only in the original container. Store the containers sealed, in a well ventilated place, away from direct sunlight. Store in a well ventilated place, keep far away from sources of heat, naked flames and sparks and other sources of ignition. Keep containers away from any incompatible materials (Oxidizers, water)

Specific end use(s).

Information not available.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

8.1. Control parameters.

During the risk assessment process, it is essential to take into consideration the ACGIH occupational exposure levels for inert particulate otherwise classified (PNOC respirable fraction: 3 mg/m3; PNOC inhalable fraction: 10 mg/m3). For values above these limits, use a P type filter, whose class (1, 2 or 3) must be chosen according to the outcome of risk assessment.

8.2. Exposure controls.

Comply with the safety measures usually applied when handling chemical substances.


In the case of prolonged contact with the product, protect the hands with penetration-resistant work gloves (see standard EN 374).

Work glove material must be chosen according to the use process and the products that may form. Latex gloves may cause sensitivity reactions.


Wear category II professional long-sleeved overalls and safety footwear (see Directive 89/686/EEC and standard EN ISO 20344). Wash body with soap and water after removing protective clothing.


Wear airtight protective goggles (see standard EN 166).


If the threshold value (e.g. TLV-TWA) is exceeded for the substance or one of the substances present in the product, wear a type FFP1 or higher class face mask if otherwise required by the risk assessment (see standard EN 149).

Respiratory protection devices must be used if the technical measures adopted are not suitable for restricting the worker's exposure to the threshold values considered. The protection provided by masks is in any case limited.

If the substance considered is odourless or its olfactory threshold is higher than the corresponding TLV-TWA and in the case of an emergency, wear open-circuit compressed air breathing apparatus (in compliance with standard EN 137) or external air-intake breathing apparatus (in compliance with standard EN 138). For a correct choice of respiratory protection device, see standard EN 529.

Stability and reactivity


Information not available.

Chemical stability.

Product stable under recommended storage condition for 1 year.

Possibility of hazardous reactions.

Information not available.

Conditions to avoid.

Warm, humidity, direct sunlight

Incompatible materials.

Oxidizers, water

Hazardous decomposition products.

Nitrogen and carbon oxides

Disposal considerations

Waste treatment methods.

Reuse, when possible. Neat product residues should be considered special non-hazardous waste.

Disposal must be performed through an authorised waste management firm, in compliance with national and local regulations.

Avoid littering. Do not contaminate soil, sewers and waterways.

Solid residues may be suitable for disposal in an authorised landfill site.


Contaminated packaging must be recovered or disposed of in compliance with national waste management regulations