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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Referenceopen allclose all

Reference Type:
other: predicted data
Title:
No information
Author:
Gedeon Richter Plc. Health and Safety Department
Year:
2015
Bibliographic source:
QSAR Toolbox 3.1.0.21
Reference Type:
other: predicted data
Title:
No information
Author:
Gedeon Richter Plc. Health and Safety Department
Year:
2015
Bibliographic source:
T.E.S.T. version 4.1

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: REACH guidance on QSARs R.6, May/July2008

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
3.524 mg/L
Nominal / measured:
estimated

Any other information on results incl. tables

Software Database / Method Endpoint Test duration Species Predicted value
QSAR Toolbox Aquatic Japan MoE LC50 96 h Oryzias latipes 10 mg/L
T.E.S.T. Group Contribution Method LC50 96 h Fathead minnow 1,08 mg/L
T.E.S.T. FDA Method LC50 96 h Fathead minnow 3,81 mg/L
T.E.S.T. Nearest neighbor method LC50 96 h Fathead minnow 1,53 mg/L
T.E.S.T. Consensus method LC50 95 h Fathead minnow 1,2 mg/L
Inferential result  3,524 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
According to (Q)SAR modells: QSAR Toolbox, T.E.S.T. the predicted values indicated that levodione is hazardous to fishes. The result meets the requirement of Aquatic Acute Category 2.