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EC number: 486-670-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
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- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Sediment toxicity
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- Additional toxicological data

Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Nov 8, 2007 - Dec 13, 2007
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. The substance is adequately characterised. Deviations were reported. The study was conducted according to the approved study protocol with 4 changes In the opinion of the Study Director, the validity of the results was not adversely affected by these changes. The substance is adequately characterised. Therefore full validation applies.
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The study was conducted according to the approved study protocol with 4 changes:
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- See Annex 6 of the full report
- Type of method:
- column elution method
Test material
- Reference substance name:
- NOREENAL
- IUPAC Name:
- NOREENAL
- Test material form:
- other: Liquid
- Details on test material:
- colourless translucent liquid.
The batch number was reported as 862036
It was stored at room temperature protected from direct sun light
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- ca. 34.8 mg/L
- Temp.:
- 21 °C
- pH:
- >= 7.01 - <= 7.05
- Details on results:
- Experiment n°1 - 25 mL/h flow rate (See Table 4)
A 1.0060 g sand portion was coated with 167.9 mg of test item (See Protocol deviation n°2). A sample of 0.3202 g was introduced in the micro-column. Analytical assessments of the coated sand showed that the micro-column was thus charged with approximately 25 mg of test item.
About 0.6 mg of the test item was controlled to be voided in the rinsed volume (15 mL).
A total of five successive samples were submitted to the analysis which corresponded to the elution over a 6-hour period. All of them served for the calculation of the hydrosolubility.
Mean concentration in water = 37.4 mg/L with a standard deviation of 2.1 mg/L.
pH of the resulting solution was measured as 7.01.
Experiment n°2 - 13 mL/h flow rate (See Table 5)
The volume of water was renewed in the reservoir and in the micro-column, using the same coated sand as for the first experiment, and the system was allowed to stand for 2 hours. The flow rate was adjusted to 12.5 mL/h. The system was considered as free from any insoluble material, and the system was not rinsed (See Protocol deviation n°3).
A total of five successive samples were submitted to the analysis which corresponded to the elution over a 9-hour period: the first sample was collected after 1 hour of elution, and the last four were collected at 2-hour intervals. All the five samples served for the calculation of the hydrosolubility.
Mean concentration in water = 32.2 mg/L with a standard deviation of 2.1 mg/L.
pH of the resulting solution was measured as 7.05.
The second value did not differ by more than 30 % to the first one and mean hydrosolubility of 34.8 mg/L was considered as valid.
Any other information on results incl. tables
Table : Samples collected from the micro-column at 25 mL/h flow rate – Raw data and calculations
Sample n° |
Dilution rate |
Area |
Measured mg/L(1) |
mg/L in water(2) |
1 |
1/20 |
125136.06 |
4.97 |
39.8 |
2 |
120 |
120388.67 |
4.77 |
38.2 |
3 |
1/20 |
121304.72 |
4.81 |
38.5 |
4 |
1/20 |
109159.57 |
4.31 |
34.5 |
5 |
1/20 |
114064.16 |
4.51 |
36.1 |
(1) As measured in the diluted chloroform phase resulting from a 2/5 concentration of the aqueous phase
(2) Recovery was considered as total
Table :Samples collected from the micro-column at 13 mL/h flow rate – Raw data and calculations
Sample n° |
Dilution rate |
Area |
Measured mg/L(1) |
mg/L in water(2) |
1 |
1/20 |
111077.79 |
4.39 |
35.1 |
2 |
1/20 |
101305.38 |
3.98 |
31.9 |
3 |
1/20 |
101844.19 |
4.01 |
32.0 |
4 |
1/20 |
92880.93 |
3.64 |
29.1 |
5 |
1/20 |
103179.16 |
4.08 |
32.7 |
(1)As measured in the diluted dichloromethane phase resulting from a 2/5 concentration of the aqueous phase
(2)Recovery was considered as total
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
Mean hydrosolubility 34.8 mg/L - Executive summary:
Phytosafe study number
07-42-050-ES
Title
GLP analysis of NOREENAL: hydrosolubility
Test item
NOREENAL
Code A45756, batch n°862036
Test dates
Initiation : November 8, 2007
Completion : December 13, 2007
Results
Hydrosolubility
micro-column elution method
(EEC A6)
Test at 25 mL/h 37.4 ± 2.1 mg/L
Test at 13 mL/h 32.2 ± 2.1 mg/L
Mean hydrosolubility 34.8 mg/L
Validity criteria were fulfilled: The second measure did not deviate by more than 30 % to the first one
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