Registration Dossier
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EC number: 275-156-8 | CAS number: 71048-82-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Two studies are available for the short-term toxicity of delta-damascone to fish. One study is a semi-static GLP-compliant OECD Guideline 203 study with medaka (Oryzias latipes) (Kurume Laboratory, 2009). The concentrations were analytically verified, the 96-h LC50 was 0.97 mg/L based on measured concentrations. The other study is also a semi-static GLP-compliant OECD 203 study with the same species. The 96-h LC50 was 0.977 mg/L based on nominal concentrations (Kurume Laboratory, 2007b). The most critical value is used in the assessment, which is the 96-h LC50 of 0.97 mg/L.
No data is available on long-term toxicity in fish.
No short-term study on invertebrates is available, but instead a semi-static GLP compliant, OECD Guideline 211 study is available regarding long-term toxicity of delta-damascone to Daphnia magna (Huntingdon Life Sciences Ltd, 2009c). The concentrations were analytically verified and the 21-d NOEC for reproduction was 0.35 mg/L. This value is used in the assessment.
One GLP compliant OECD Guideline 201 study is available for growth inhibition of delta-damascone to Pseudokirchneriella subcapitata (Huntingdon Life Sciences Ltd, 2009d). The concentrations were analytically verified. The 72-h EbC50 was 2.47 mg/L, the 72-h ErC50 and NOErC were 4.54 mg/L and 0.883 mg/L, respectively. The effect concentrations based on growth rate are used in the assessment.
One GLP-compliant OECD Guideline 209 respiration inhibition study with micro-organisms is available for delta-damascone (Huntingdon Life Sciences Ltd, 2009e). The 3-h EC50 was 241 mg/L, this value is used in the assessment.
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