Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report Date:
1998

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
Deviations:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
semi-solid (amorphous): gel
Radiolabelling:
no

Results and discussion

Total recovery of test substance (in %)open allclose all
% Recovery:
95.1
pH:
4
Temp.:
50 °C
Duration:
15 min
% Recovery:
93.6
pH:
7
Temp.:
50 °C
Duration:
15 min
% Recovery:
94.9
pH:
9
Temp.:
50 °C
Duration:
15 min
Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0.019 h-1
DT50:
36.6 h
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0.017 h-1
DT50:
40.1 h
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:
pH:
4
Temp.:
35 °C
Hydrolysis rate constant:
0.003 h-1
DT50:
257.6 h
Remarks on result:
other:
pH:
4
Temp.:
25 °C
Hydrolysis rate constant:
0.001 h-1
DT50:
42.8 d
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:
pH:
4
Temp.:
20 °C
Hydrolysis rate constant:
0 h-1
DT50:
88.6 d
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:
pH:
4
Temp.:
12 °C
Hydrolysis rate constant:
0 h-1
DT50:
298.8 d
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:

Applicant's summary and conclusion

Validity criteria fulfilled:
yes