Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1969
Report date:
1969

Materials and methods

Principles of method if other than guideline:
according to BASF-internal standard
GLP compliance:
no
Test type:
other: Inhalation hazard test

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenethylamine
EC Number:
200-574-4
EC Name:
Phenethylamine
Cas Number:
64-04-0
Molecular formula:
C8H11N
IUPAC Name:
2-phenylethanamine
Test material form:
liquid
Details on test material:
Name of the test substance used in the study report: 2-Phenylethylamin

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: vapour
Remarks on duration:
3 and 8 h
Concentrations:
Saturated vapour concentration 2 mg/L
No. of animals per sex per dose:
3 h: 12
8 h: 6

Results and discussion

Mortality:
3 h: 0/12
8 h: 1/6
Clinical signs:
other: severe attempts to escape, severe mucosal irritations, dyspnea
Gross pathology:
nothing abnormal detected

Applicant's summary and conclusion