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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
other information
Study period:
11-2004 to 08-2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well reported GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
17β-hydroxy-1α-methyl-5-αandrostan-3-one acetate
EC Number:
223-768-0
EC Name:
17β-hydroxy-1α-methyl-5-αandrostan-3-one acetate
Cas Number:
4062-46-8
Molecular formula:
C22H34O3
IUPAC Name:
1-methyl-3-oxoandrostan-17-yl acetate

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Results and discussion

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
ZK 5894 had no concentration-depended inhibitory effect on the growth of Desmodesmus
subspicatus. The EbC50/72 hours (biomass) was higher than a saturated solution.
Executive summary:

The toxicity of the test substance was also studied in a growth inhibition test in the algae Desmodesmus subspicatus according to OECD201. The algal population was incubated wwith the test substance over a period of 72 hours.to a saturated solution and two dilutions (1:10, 1:100). No effect on growth as observed. Therefore, the EC50 for growth inhibition was higher than a saturated solution.

The study was conducted under GLP