Registration Dossier
Registration Dossier
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EC number: 229-912-9 | CAS number: 6834-92-0
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Schleyer WL and Blumberg JG (1982). Health, safety and|environmental aspects of soluble silicates. In Soluble|Silicates, Falcone JS (ed). ACS Symposium Series 194,|Chapter 4, 49-69.
- Title:
- No information
- Author:
- Sigrist Th, Flury K (1985). Tod durch perorale Aufnahme von Wasserglas (Natriumsilikat). Z. Rechtsmed. 94, 245-250.
Materials and methods
- Study type:
- poisoning incident
- Principles of method if other than guideline:
- Case study report
Test material
- Reference substance name:
- Disodium metasilicate
- EC Number:
- 229-912-9
- EC Name:
- Disodium metasilicate
- Cas Number:
- 6834-92-0
- Molecular formula:
- H2O3Si.2Na Soluble Silicates Category
- IUPAC Name:
- disodium oxosilanediolate
- Details on test material:
- TS-Freetext:
Although the authors state that sodium metasilicate
was used (in form of an egg preserving solution from a local
drug store), the relative low pH of 12.5 makes it more
likely that a silicate solution of a molar ratio of greater
than 1.0 was ingested. Moreover, egg preservatives typically
contain 5-36% of 3.2 SiO2/Na2O silicate (Schleyer &
Blumberg, 1982).
Constituent 1
Results and discussion
Any other information on results incl. tables
Ingestion of 500 ml of an egg-preserving solution containing sodium silicate in suicidal intention led to death of a 68 year old woman within 1 hour by suffocation. Aspiration of the vomited silicate solution caused obstruction of the lungs by precipitation of amorphous silica. The transformation of sodium silicate from liquid to solid occured in the lungs by means of the carbonic acid of expiration air.
Applicant's summary and conclusion
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