Registration Dossier

Physical & Chemical properties

Nanomaterial Zeta potential

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Administrative data

Endpoint:
nanomaterial Zeta potential
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Principles of method if other than guideline:
The isoelectric point (IEP) or point of zero zeta potential (PZC) was automatically determined using the Zeta Sizer nano ZSP with a Multi Purpose Titrator MPT2 (Malvern Instruments Ltd, Malvern, UK). The pH condition of the sample was altered by using the auto-titrator and the sample was circulated into the disposable capillary cell situated in the Zetasizer Nano for the zeta potential measurements to be made. The data was processed in a plot of the zeta potential of a sample measured as a function of pH.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: nanoform, surface-treated
Remarks:
aqueous suspension of nanomaterial
Details on test material:
Spherical particles
Particle size distribution (primary particles; number-based): Min = 5 nm, D25 = 7 nm, D50 = 8 nm, D75 = 9 nm, Max = 61 nm
Volume specific surface area: 714 m2/cm3
Zeta potential: -33.5 mV

Data gathering

Instruments:
Zeta Sizer nano ZSP with a Multi Purpose Titrator MPT2 (Malvern Instruments Ltd, Malvern, UK)

Results and discussion

Zeta potential
Zeta potential:
-33.5 mV
St. dev.:
5.25 mV
pH:
5.51
Medium:
water
Isoelectric point
Isoelectric Point:
< 0.2
Medium:
water

Applicant's summary and conclusion

Conclusions:
The zetapotential of nanosilver Sample 1 is -33,5 mV and the IEP is lower than pH 0,2 which means that it is a very stable dispersion.