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Description of key information

The handling of urea by the human body is well characterised as it is a normal product of protein catabolism and is normally produced in large quantities.

Key value for chemical safety assessment

Additional information

A waiver is proposed. Urea is produced in large quantities by the human body as a product of normal metabolism and is excreted unchanged in the urine. Further studies characterising the toxicokinetics of urea are therefore not required.

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