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EC number: 292-588-2 | CAS number: 90640-67-8
Dose (g/kg bw)
No. Died/No. Fed
Died in 1 day
No effects observed
An acute oral toxicity study was performed pre-guideline and pre-GLP with rats of unknown sex. 10% of the test substance in water was administered to the rats in doses of 3.0, 2.0, 1.0 and 0.3 g/kg bw. The LD50 is between 1000 -2000 mg/kg bw based on the results of this study.
The material was not absorbed in acutely toxic amounts.
Through rabbit skin the material was not absorbed in acutely toxic amounts. No further information.
Marked to severe pain, irritation, and permanent corneal damage
Moderate pain, irritation, and very slight residual corneal damage
10% in water
Unwashed and washed H2O
Very slight to slight pain, irritation and transient corneal injury
1% in water
Very slight initial pain
The eyes of rabbits were exposed to the test substance undiluted, and at 10% and 1% in water with and without washing the eyes. No further details on the methods. The undiluted test substance is corrosive to the eye and at 1% slight irritation is observed.
Condition of the skin
Number of applications
1 for 12 minutes
Severe hyperemia and slight denaturation
1 for 6 minutes
Moderate hyperemia and slight denaturation
1 for 3 minutes
1 for 1 minutes
No apparent effect
10% in H2O
Severe hyperemia, denaturation and slight edema
1% in H2O
The intact skin of belly or ears of rabbits were exposed to the test substance as undiluted, 10% and 1% in water. No further details on the methods. After 6 minutes exposure necrosis is seen.
Two groups of 3 rats each (of unknown sex) were exposed to the substance vapour or fume at room temperature. Inhalation was via saturated atmosphere. For one group the bath temperature was 25°C and the animals were exposed for 8.0 hours. For the second group the bath temperature was 100°C and the animals were exposed for 7.0 hours. No deaths were observed and no other effects. A strong ammoniacal odor was noticed.
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