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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: short review
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Short summary on sensitivity to TETA in Poland.

Data source

Reference
Reference Type:
publication
Title:
Dermatitis from triethylenetetramine in Poland
Author:
Rudzki, E.
Year:
1980
Bibliographic source:
Contact Dermatitis. Apr;6(3):235-6.

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Amines, polyethylenepoly-, triethylenetetramine fraction
EC Number:
292-588-2
EC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Cas Number:
90640-67-8
Molecular formula:
C6H18N4, C8H20N4
IUPAC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Test material form:
liquid

Method

Type of population:
occupational
Route of administration:
dermal

Results and discussion

Results of examinations:
Results from patch tests from different publications resulted in 20 to 50% positive response.

Applicant's summary and conclusion

Conclusions:
Sensitivity to the test substance is frequent in epoxy resin workers in Poland.
Executive summary:

In Poland, ca. 20 -50% of the patients working with epoxy resins tested positive on patch testing with Amines, polyethylenepoly-, triethylenetetramine fraction.