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EC number: 292-588-2 | CAS number: 90640-67-8
Toxicity to birds
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to birds
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a summary is provided.
- Qualifier:
- according to guideline
- Guideline:
- other: DeCino, T. J., D. J. Cunningham, and E. W. Schafer: Toxicity of DRC-1339 to starlings. J. Wildl. Manage. 30, 249 (1966).
- Qualifier:
- according to guideline
- Guideline:
- other: Schafer, E. W., Jr.: The acute oral toxicity of 369 pesticidal, pharmaceutical and other chemicals to wild birds. Toxico!. Appl. Pharmacol. 21, 315 (1972).
- Qualifier:
- according to guideline
- Guideline:
- other: Thompson, W. R: Use of moving averages and interpolation to estimate median effective dose. Bacteriol. Rev. 11, 115 (1948).
- Qualifier:
- according to guideline
- Guideline:
- other: Thompson, W. R., and C. S. Weil: On the construction of tables for moving average interpolation. Biometrics 8, 51 (1952).
- Qualifier:
- according to guideline
- Guideline:
- other: Wei!, C. S.: Tables for convenient calculation of median effective dose (LD50 or ED50) and instructions in their use. Biometrics 8, 249 (1952).
- GLP compliance:
- no
- Duration (if not single dose):
- 18 h
- Dose descriptor:
- LD50
- Effect level:
- > 110 mg/kg bw
- Conc. / dose based on:
- not specified
- Basis for effect:
- mortality
- Executive summary:
The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more of 68 species of wild and domestic birds was determined by standardized testing procedures. Redwinged blackbirds were the most sensitive of the bird species tested on a large number of chemicals, and an index based on redwing toxicity and repellency may provide an appropriate indication of the probability of acute avian poisoning episodes. Avian repellency and toxicity were not positively correlated (i.e. toxicity varied independently with repellency).
For triethylene tetraamine the LD50 was estimated based on the food consumption measured over a period of 18 hours. The LD50 is estimated at 101 mg/kg.
Reference
Description of key information
Key value for chemical safety assessment
Additional information
Wild-trapped birds were preconditioned to captivity for 2 to 6 weeks and were usually dosed by gavage with solutions or suspensions of the test chemical in propylene glycol. The LD50 was estimated based on the food consumption measured over a period of 18 hours. The LD50 (18 h) is estimated at 101 mg/kg bw.
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