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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: dermal

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Administrative data

Endpoint:
repeated dose toxicity: dermal
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Publication with limited reporting details; test substance was administered (skin application) weekly, and only skin section was examined.

Data source

Reference
Reference Type:
publication
Title:
Tests on mice for evaluating carcinogenicity.
Author:
Hodge, H.C., Maynard, E.A., Downs, W.L., Ashton, J.K. and Salerno, L.L.
Year:
1966
Bibliographic source:
Toxicology and applied pharmacology 9, pg.583-596.

Materials and methods

Test material

Constituent 1
Reference substance name:
Bis(2-ethylhexyl) adipate
EC Number:
203-090-1
EC Name:
Bis(2-ethylhexyl) adipate
Cas Number:
103-23-1
IUPAC Name:
bis(2-ethylhexyl) adipate

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion