Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

One study investigating the toxicity to terrestrial organisms is available for Bis(2-propylheptyl) hexanedioate (DPHA). The study was performed according to GLP and OECD guideline 207 using Eisenia foetida as test organism (Xiaoqian 2015). A test substance concentration of 1000 mg/kg was tested in a limit test. No mortality in the treatment as well as no significant difference in body weight between treatment and control were observed during an exposure time of 14 days. Thus, the 14d-LC50 value is determined to be > 1000 mg/kg. Based on this result it can be concluded that DPHA is not toxic to terrestrial organisms at relevant environmental concentrations.

In accordance with Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.4 further studies on the effects on terrestrial organisms does not have to be conducted since the chemical safety assessment indicates that there is no need. The test substance is readily biodegradable and will therefore not persist in soil for an extended period of time. Furthermore, the substance is not toxic to aquatic organisms up to the limit of water solubility and available data indicate that DPHA is not bioaccumulative. Due to its high adsorption potential DPHA is considered to be immobile in soil and uptake by roots via pore-water is not expected. Studies with aquatic microorganisms showed that DPHA is rapidly degraded and show no inhibitory effect. Hence, the risk the substance poses to terrestrial plants and microorganisms is considered to be low and a study is not considered to be necessary.