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EC number: 940-510-9
CAS number: 103043-58-9
One study investigating the toxicity to terrestrial organisms is
available for Bis(2-propylheptyl) hexanedioate (DPHA). The study was
performed according to GLP and OECD guideline 207 using Eisenia
foetida as test organism (Xiaoqian 2015). A test substance
concentration of 1000 mg/kg was tested in a limit test. No mortality in
the treatment as well as no significant difference in body weight
between treatment and control were observed during an exposure time of
14 days. Thus, the 14d-LC50 value is determined to be > 1000 mg/kg.
Based on this result it can be concluded that DPHA is not toxic to
terrestrial organisms at relevant environmental concentrations.
In accordance with Regulation (EC) No. 1907/2006, Annex X, Column
2, 9.4 further studies on the effects on terrestrial organisms does not
have to be conducted since the chemical safety assessment indicates that
there is no need. The test substance is readily biodegradable and will
therefore not persist in soil for an extended period of time.
Furthermore, the substance is not toxic to aquatic organisms up to the
limit of water solubility and available data indicate that DPHA is not
bioaccumulative. Due to its high adsorption potential DPHA is considered
to be immobile in soil and uptake by roots via pore-water is not
expected. Studies with aquatic microorganisms showed that DPHA is
rapidly degraded and show no inhibitory effect. Hence, the risk the
substance poses to terrestrial plants and microorganisms is considered
to be low and a study is not considered to be necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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