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Long-term toxicity to fish

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Description of key information

No data on long-term toxicity to fish is available. Considering all relevant ecotoxicological information available, long-term toxicity for fish is not expected.

Key value for chemical safety assessment

Additional information

No experimental data on long-term toxicity to fish are available Hexanoic acid, 2-ethyl-, C16-18 alkyl esters (CAS No. 90411-68-0). The chemical safety assessment according to Annex I of Regulation (EC) 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2, no further long-term toxicity test to fish is proposed.

Based on the available data, no effects were observed in short-term studies with fish, aquatic invertebrates and algae. Moreover, no effects were observed in two chronic read across studies with Daphnia magna according to OECD 211 (NOELR/NOEC > 1 mg/L). As there was no sign that invertebrates are less sensitive than fish in the short term tests, it cannot be expected that a long-term test with fish will generate different results than the existing long-term data with invertebrates. Due to its ready biodegradability it is not likely that aquatic organisms are exposed to the test substance since it will be ultimately degraded in sewage treatment plants. Thus, based on the above mentioned results, it can be concluded that Hexanoic acid, 2-ethyl-, C16-18 alkyl esters (CAS No. 90411-68-0) does not show any chronic toxicity to fish up to the limit of water solubility. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term toxicity test with fish is required.