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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96-h LC50 in the freshwater fish Oncorhynchus mykiss is 52 mg/l. The 96 h LC50 is 89 mg/L in the marine fish species Mugil cephalus.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
52 mg/L

Marine water fish

Marine water fish
Effect concentration:
89 mg/L

Additional information

A GLP-compliant guideline study (EPA-660/3-75-009) is available for propylene oxide, reporting a 96 h LC50 value of 52 mg/L in the freshwater species Salmo gairdneri (new name: Oncorhynchus mykiss) (Shell Research Ltd., 1986). The only saltwater species reported is the common mullet (Mugil cephalus) which shows a similar sensitivity to the freshwater species, having a 96 h LC50 of 89 mg/L (Crews, 1974).