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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
explosive properties of explosives
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Exerimental data and the functional groups of Docusate Sodium were considered in the assessment.
Qualifier:
according to guideline
Guideline:
EU Method A.14 (Explosive properties)
Deviations:
no
GLP compliance:
no
Key result
Parameter:
other: structure
Remarks on result:
other: based on the structure, it can be excluded that the registered substance has explosive properties

According to the chemical structure and the list of reactive groups that could have explosive properties (Bretherick’s Handbook of Reactive Chemical Hazards, Butterworths, 4th edition) it can be excluded that Docusate Sodium has explosive properties.

Interpretation of results:
non explosive
Remarks:
Migrated information
Conclusions:
Docusate Sodium is non explosive.
Executive summary:

As stated in the EU method A.14, section 1.1 “the tests need not to be performed when available thermodynamic information (e.g. heat of formation, heat of decomposition) and/or absence of certain reactive groups in the structural formula establishes beyond reasonable doubt that the substance is incapable of rapid decomposition with evolution of gases or release of heat (i.e. the material does not present any risk of explosion).”

According to the chemical structure and the list of reactive groups that could have explosive properties (Bretherick’s Handbook of Reactive Chemical Hazards, Butterworths, 4thedition) it can be excluded that Docusate Sodium has explosive properties.

Furthermore the determination of the thermal stability of the test substance by DSC (Differential Scanning Calorimetry) showed that between 30°C and 450°C the decomposition energy is about -200 kJ/kg and therefore well below the limit of -500 kJ/kg given in the Regulation (EC) No 1272/2008 (CLP) Chapter 2.1.4.3. (c).

Description of key information

non-explosive

Key value for chemical safety assessment

Explosiveness:
non explosive

Additional information

As stated in the EU method A.14 (2008), section 1.1 “the tests need not to be performed when available thermodynamic information (e.g. heat of formation, heat of decomposition) and/or absence of certain reactive groups in the structural formula establishes beyond reasonable doubt that the substance is incapable of rapid decomposition with evolution of gases or release of heat (i.e. the material does not present any risk of explosion).”

According to the chemical structure and the list of reactive groups that could have explosive properties (Bretherick’s Handbook of Reactive Chemical Hazards, Butterworths, 4th edition) it can be excluded that Docusate Sodium has explosive properties. Furthermore the determination of the thermal stability of the test substance by DSC (Differential Scanning Calorimetry) showed that between 30°C and 450°C the decomposition energy is about -200 kJ/kg and therefore well below the limit of -500 kJ/kg given in the Regulation (EC) No 1272/2008 (CLP) Chapter 2.1.4.3. (c).

Justification for classification or non-classification

Based on measured decomposition energy of -200 kJ/kg and the molecular structure which lacks functional groups related to explosiveness, Docusate Sodium is considered to be non-explosive. Hence. no classification and labelling is needed according to GHS and CLP.