Registration Dossier
Registration Dossier
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EC number: 211-162-9 | CAS number: 631-61-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to microorganisms: Weight of evidence: The EC50 is estimated to be between 6770 mg/L. Read-across approach from experimental data on analogues Sodium Acetate and Ammonium Propionate.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 6 770 mg/L
- EC10 or NOEC for microorganisms:
- 490.69 mg/L
Additional information
Weight of evidence: Read-across approach from experimental data on analogues Sodium Acetate and Ammonium Propionate.
Read-across from Sodium Acetate data:
16 h-EC50 for Pseudomonas putida in a static test was 7.2 g/L, and EC10 was 3.5 g/L. Based on these results and the molecular weights, the read-across approach was applied and the 16h-EC50 for Pseudomonas putida for Ammonium acetate is calculated to be 6.77 g/L, and EC10 is estimated to 3.29 g/L under test conditions.
Read-across from Ammonium Propionate data:
17 h-EC50 for Pseudomonas putida was 890 mg/L, EC10 was 580 mg/L, and EC90 was 1200 mg/L. Based on these results and the molecular weights, the read-across approach was applied and the 17h-EC50 for Pseudomonas putida with the substance Ammonium acetate is estimated to 752.95 mg/L, EC10 is estimated to 490.69 mg/L, and EC90 is estimated to 1015.21 mg/L under test conditions.
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