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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The EC50 value was determined as 69.87 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
69.87 mg/L

Additional information

In an activated sludge test with tetrahydromethylphthalic anhydride (MTHPA) an EC50 value was determined as 69.87 mg/L.

An accurate NOEC value was not determined. The NOEC was lower than the investigated lowest concentration level of 10 mg/L.

The respiration rates were inhibited and influenced dose dependently in the whole concentration range, the observed inhibition (17.6 %) at the lowest examined concentration level of 10 mg/L was evaluated as an unequivocal effect caused by the test item.