Registration Dossier
Registration Dossier
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EC number: 277-452-2 | CAS number: 73398-61-5
Endpoint summary
Administrative data
Description of key information
Additional information
Due to the properties of the category members Fatty Acid Glycerides, their bioaccumulation in aquatic organisms is assumed to be low.
As Fatty Acid Glycerides are readily biodegradable and have a very low water solubility (< 1 mg/L), only low concentrations in the aquatic environment and thus low concentrations in aquatic organisms can be expected.
FurthermoreFatty Acid Glycerides (mono-, di-, and tri-esters of fatty acids with glycerol) have in mammals a common metabolic fate that involves stepwise hydrolysis to the fatty acids and glycerol. Fatty acids and glycerol feed into physiological pathways like the citric acid cycle, sugar synthesis, and lipid synthesis. Furthermore mono- and diglycerides have an amphiphilic character and can be part of biological membranes or act as emulsifier and thus, are naturally present in all living organism. Fatty Acid Glycerides are stored deliberately in the fatty tissue as energy source and metabolized if needed.
Hence, in case bioaccumulation occurs, bioaccumulation in animal tissue is nonhazardous due to the metabolic fate of the Fatty Acid Glycerides (use as energy source).
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