Registration Dossier
Registration Dossier
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EC number: 246-770-3 | CAS number: 25265-71-8
Endpoint summary
Administrative data
Description of key information
Additional information
The calculated half life of dipropylene glycol in air is 0.341 days with an OH radical concentration of 1.5E6 OH/cm3 ( AOPWIN, 2000).
In accordance with column 2 of REACH Annex VIII, the hydrolysis test does not need to be conducted as the substance is readily biodegradable. Furthermore, ethers and glycols are generally known to be resistant to hydrolysis (Harris, J.C., 1990). Therefore, dipropylene glycol is not expected to undergo hydrolysis under environmentally relevant conditions.
Dipropylene glycol is capable of being degraded under aerobic conditions by bacteria in water. Results from biodegradation screening tests show that dipropylene glycol is ready biodegradable in water (>80% after 28 days) (West et al., 2007). Significant biodegradation (>20%) was found in a simulation test with natural seawater after 64 days (West et al., 2007). Therefore dipropylene glycol is not expected to persist in water or marine environments. Simulation studies with sediment and/or soil are not available.
The rate constants used in the assessment are (EUSES calculations):
Degradation for hydrolysis |
6.93E-07 d-1 |
Degradation for photolysis |
6.93E-07 d-1 |
Degradation in air |
0.341 d-1 (QSAR calculation) |
Degradation in the STP |
24 d-1 |
Biodegradation in water |
0.0462 d-1 |
Biodegradation in sediment |
2.31E-03 d-1 |
Biodegradation in soil |
0.0231 d-1 |
Based on the result of the octanol/water partition coefficient (Log Kow = -0.46) and from results of the bioaccumulation study with carp species dipropylene glycol is not expected to significantly accumulate in aquatic organisms (BCF 0.3 to 4.6 l/kg) (MITI, 1992).
Based on the result of the octanol/water partition coefficient (Log Kow of -0.46) dipropylene glycol is expected to have a low potential for adsorption/desorption.The Koc value calculated from the octanol-water partition coefficient using the equation from the TGD (non-hydrophobics) is 6.04 (log value = 0.78).
If released into the environment, dipropylene glycol will preferentially partition into water (46.1%) and soil (53.7%) (Mackay, 1991). Volatility is not expected to be a significant fate process due to its low vapor pressure and high water solubility.
Using EUSES calculation, the Henry's law constant is 9.07E-04 Pa.m3/mol at environmental relevant temperature.
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