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Toxicity to microorganisms

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Description of key information

Toxicity to microorganisms

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

A laboratory test was carried out with Kronitex TCP to evaluate the effect of the test item on microorganisms by measuring the respiration rate.


The NOEC was determined to be 1000 mg/L.


The NOEC for respiration rates was not based on the results of a statistical analysis, but it is biologically justified. The respiration rates were not inhibited and influenced dose dependently in the whole concentration range, and the observed slight inhibition (14.6 %) at the concentration level of 1000 mg/L was evaluated as reflecting the biological variability in the test. The calculated respiration rate, 0.350 (at 1000 mg/L) was below the historical control data range (0.522 +/- 0.069), but the deviation from the control was within +/- 15 %, it can be considered as a biological variability of the test system.