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EC number: 809-930-9
CAS number: 1330-78-5
Short term toxicity to Algae
studies are available for inspection as follows;
capricornutum were exposed to a 2500 µg/L accommodated fraction (WAF)
loading rate of tricresyl phosphate (TCP) and evaluated for effects on
cell density, area under the growth curve and growth rate. The 72 and
96-hour EL50, based on cell density, biomass and growth rate, was >2500
µg/L. The 72-hour NOAEL for cell density, biomass and growth rate was
2400, >2500 and >2500 µg/L, respectively, based on a calculated EL10
value. The 96 hour NOAEL, based on cell density, biomass and growth rate
was 2500 µg/L.
on 'Reaction mass of bis(methylphenyl) phenyl phosphate and diphenyl
tolyl phosphate and tris(methylphenyl) phosphate', Desmodesmus
subspicatus was exposed for a period of 72 h to test solutions with
concentrations, nominally 0.0122, 0.0243, 0.0486, 0.0972 and 0.194 mg/L.
The cell densities were measured at 24 hour intervals. Inhibition of the
algal population was measured as reduction in growth rate (index r),
relative to control cultures grown under identical conditions. Growth
rates were also used to calculate a No Observed Effect Concentration and
a Lowest Observed Effect Concentration according to Williams Multiple
Sequential t-Test Procedure. The following values were determined: ErC
50: 0.4042 mg/L and ErC 10: 0.016 mg/L. As analytical monitoring was
carried out, the results are expressed in terms of geometric mean
measured concentrations. Effective concentrations ranged from 65.5-69.1%
of nominal values at 0 hours, and from 49.0-52.1% of nominal values at
72 hours, respectively. This toxicity study is classified as acceptable
and satisfies the guideline requirements for the acute algae study.
toxicity at the limit of solubility in water was therefore noted in
either study, and it is proposed that the substance does not cause
algistatic effects at the limit of solubility.
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