Registration Dossier
Registration Dossier
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EC number: 219-787-9 | CAS number: 2530-87-2
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
Reference
Description of key information
Adsorption/desorption:
log Koc [(3-chloropropyl)trimethoxysilane]: Low potential for adsorption due to rapid hydrolysis in contact with water
log Koc [(3-chloropropyl)silanetriol] = 0.45 (calculated)
Key value for chemical safety assessment
Additional information
The substance hydrolyses rapidly to substances which have low log Kow values (<3) and thus have low potential for adsorption, and the requirement for testing is waived. The parent substance itself also has a log Kow value <3.
For environmental exposure assessment, adsorption is predicted for the silanol hydrolysis product using the ‘non-hydrophobics’ log Kow-based prediction method for log Koc (Sabljic et al., 1995).
The relevant equation is:
Log Koc = 0.52 log Kow + 1.02
Therefore, log Koc for the silanol hydrolysis product = 0.45
Reference:
Sabljic, A, Güsten H, Verhaar H, Hermens J (1995) QSAR modelling of soil sorption. Improvements and systematics of log KOC vs. log KOW correlations. Chemosphere Volume 31, Issues 11–12, December 1995, Pages 4489–4514.
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